Pinky and the Brain is an Emmy-winning animated television series and spinoff of Animaniacs starring Pinky and the Brain. The show ran from 1995 to 1999 on Kids' WB!. The pair later spun-off into their second and last series, Pinky, Elmyra & the Brain and paired with Tiny Toons star, Elmyra Duff. Pinky and the Brain first appeared in 1993 as a recurring segment on the show Animaniacs. From 1995 to 1998, Pinky and the Brain were spun-off into their own Emmy-award-winning show on The WB Television Network, Steven Spielberg Presents Pinky and the Brain, with 65 episodes produced by Steven Spielberg and Warner Bros. Animation. Later, they appeared in the unsuccessful series, Steven Spielberg Presents Pinky, Elmyra & the Brain. Pinky and Brain are genetically enhanced laboratory mice who reside in a cage in the Acme Labs research facility. Brain is self-centered and scheming; Pinky is good-natured but feebleminded. In each episode, Brain devises a new plan to take over the world, which ultimately ends in failure, usually due to Pinky's idiocy or the impossibility of Brain's plan. In common with many other Animaniacs shorts, many episodes are in some way a parody of something else, usually a film or novel. Nearly every episode opens with the following dialogue: Pinky: "Gee, Brain, what do you want to do tonight?" The Brain: "The same thing we do every night, Pinky—try to take over the world!" Premise Most of the Pinky and the Brain episodes occur in the present time at Acme Labs, located in some large American metropolitan city near a bridge, presumably San Francisco to tie in with Animaniacs and the Warner Brothers studio lot. However, several episodes took place in historical times, with Pinky and the Brain under the laboratory care of some scientifically-minded person, including Merlin,[1] H.G. Wells[2] and Ivan Pavlov.[3] The bulk of every episode involves one of Brain's plans for world domination with Pinky's assistance and the ultimate failure of that plan. One centers on his rival Snowball's plan to take over the world using Microsponge.[4] Another episode features Brain's single day where he tries to do anything but take over the world: in the end, a group of people vote that he should take over the world on the one day he does not want to.[5] There is very little continuity between episodes outside of the common fixtures of the mice, though some plans for world domination from early episodes are subsequently referred to in later seasons (for example, Brain's "human suit" used in "Win Big"[6] reappears when Brain faces Snowball in "Snowball."[4] Both Pinky and the Brain, white mice kept as part of Acme Labs' experimentation, have undergone significant genetic alteration; as per the show's title lyrics, "their genes have been spliced" which gives the two mice amplified intelligence over that of a typical mouse, the ability to talk to humans, and anthropomorphism. "Project B.R.A.I.N." suggests that the gene splicing occurred on September 9, 1995,[7] coincident to the first full episode of Pinky and the Brain. The episode "Brainwashed" states that the gene splicing was done by Dr. Mordough, along with SnowbAlthough Pinky and the Brain plan to conquer the world, they do not show much antagonism; in a Christmas special Pinky even wrote to Santa that Brain had the world's best interests at heart.[9] all the hamster and Precious the cat, using the Acme "Gene Splicer and Bagel Warmer."[8
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